胥保华

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胥保华

职称:教授

邮箱:bhxu@sdau.edu.cn

办公室电话:0538-8241462

http://www.zgkjcx.com/Article/ShowArticle.asp?ArticleID=17149

个人简介

胥保华,男,1965年生,博士,教授,博士生导师,泰山产业领军人才,山东农业大学“1512工程”第一层次。现任山东农业大学动物科技学院教授委员会主任,国家现代农业产业技术体系岗位科学家,教育部动物生产类教学指导委员会委员,农业部畜禽遗传资源委员会蜜蜂专委会委员,山东省优秀科技工作者。长期从事蜜蜂科学研究与教学工作,担任《营养与食品科学》、《中国蜂业》、《蜜蜂杂志》、《山东农业科学》、《山东畜牧兽医》等期刊编委。

教育经历

1999 - 2003 , 农学博士 , 特种经济动物饲养 , 浙江大学

1988 - 1991 , 农学硕士 , 动物生产 , 山东农业大学

1983 - 1988 , 农学学士 , 畜牧 , 山东农业大学

工作经历

1991 - 至今 , 讲师,副教授, 教授,山东农业大学动物科技学院

荣誉奖励

山东省优秀科技工作者 , 2000

执教课程

蜜蜂养殖学,蜜蜂生产学(本科生)

高级特种经济动物饲养学,特种经济动物资源及养殖技术(研究生)

研究领域

本实验室主要研究领域

1. 蜜蜂营养生理

2. 蜜蜂抗逆生物学

3. 蜜蜂遗传育种

所率领的科研团队在中华蜜蜂(Apis cerana cerana)抗逆生物学研究领域处国际领先地位,对导致中华蜜蜂具有较强抗逆性的生物学分子机制,尤其是抗逆基因进行了结构分析、表达特性分析、重组蛋白功能特性分析等研究,发表该领域SCI论文70余篇。在应用研究领域,胥保华教授团队主要开展了蜜蜂健康养殖技术研究,倡导蜜蜂福利饲养理念,系统开展了蜜蜂营养需要研究,提出了蜜蜂周年阶段营养需要建议标准,发表该领域学术论文40余篇。主持制定了《蜜蜂群势增长期饲养技术规范》等 9项蜂业标准,获国家专利11项。

承担的科研项目

1.泰山产业领军人才工程(高效生态农业创新类)项目“蜜蜂健康高效生态养殖与优质蜂产品生产关键技术研究与集成示范”(LJNY202003),2020~2023200万。

2.国家蜂产业技术体系建设岗位科学家(CARS-44,营养与饲料岗位)2008~2025, 70万元/年。

3.国家自然科学基金“中华蜜蜂小分子热激蛋白基因的功能分析(31572470)”,2016~201978万元。

4.国家自然科学基金“中华蜜蜂GSTs基因的表达调控及抗氧化功能分析(31172275)”,2012~2015, 60万元。

5.山东省农业良种工程“基于浙江浆蜂的优质抗逆配套系选育(2017LZN006)”,2017~2020100万元。

6.山东省农业良种工程“优质高产蜜蜂及家蚕新品种选育”,2014~2016180万元。

7.公益性行业(农业)专项“饲料营养价值与畜禽饲养标准研究与应用(2009003006)”,2009~2013, 78万元。

8.鲁渝科技合作项目“山地中蜂良种培育与生态养殖(2019LYXZ020)”,2019~202020万元。

9.公益性行业(农业)专项“不同蜜蜂生产区抗逆增产技术体系研究与示范(No.nyhyzx07-041)”,2007~2010, 34万元。

获得的专利

1.胥保华,陈宜斗,李有志,.一种中华蜜蜂巢蜜生产框架. 实用新型专利,专利号:ZL 2015 2 0702580.9

2.胥保华,王颖,马兰婷,.一种单箱体蜂群使用的蜜蜂饲喂装置.实用新型专利, 专利号:ZL 2015 2 0243589.8

3.胥保华,陈宜斗,王颖,.一种中华蜜蜂定地饲养蜂箱. 实用新型专利,专利号:ZL 2014 2 0503642.9

4.胥保华,吴福明,王颖,.一种箱底自控式蜜蜂饲喂器. 实用新型专利,专利号:ZL 2014 2 0502278.4

5.胥保华,吴福明,王颖,.一种可调式蜜蜂饲料饲喂器. 实用新型专利,专利号:ZL 2014 2 0503138.9

6.胥保华,王颖,马兰婷,.一种蜜蜂室内饲养装置. 实用新型专利,专利号:ZL 2014 2 0503643.3

7.胥保华,王会明,康明江轴针式自控蜜蜂饲喂器. 实用新型专利,专利号:ZL 2010 2 0665212.9

8.常仲乐,毕建杰,康明江,.便调式蜜蜂人工授精仪显微镜固定架. 实用新型专利,专利号:ZL 2010 2 0503060.2

9.常仲乐,毕建杰,康明江,.蜜蜂人工授精仪注射器角度调节装置. 实用新型专利,专利号:ZL 2010 2 0503053.2

10.胥保华,赵晓冬,王颖,.一种用于废旧蜂脾的绿色集约化处理装置. 实用新型专利,专利号:ZL 2017 2 1430044.3

11.胥保华、张卫星、王颖、崔学沛、王红芳、刘振国. 一种蜜蜂巢脾熏蒸装置. 实用新型专利,专利号:ZL 2019 2 0574220.3

12.WANG, Hongfang; XU, Baohua; LIU, Zhenguo; WANG, Ying; MA, Lanting; CUI, Xuepei and WEI, Wei FERMENTED FEED FOR HONEY BEE COLONY DURING SPRING MULTIPLICATION, Patent number: 2020100410. (王红芳,胥保华,刘振国,王颖,马兰婷,崔学沛,魏伟. 一种蜂群春繁期发酵饲料,澳大利亚革新专利证书号:2020100410)

13.郭兴启、赵光栋、王琛、胥保华、崔学沛 中华蜜蜂AccCDK5基因及AccCDK5r1基因及其应用. 发明专利,专利号:ZL 2016 1 1067992

14.郭兴启,李桂林,胥保华,王颖,王红芳,刘振国. 蜜蜂抗逆相关基因NF-Y及其应用.发明专利,专利号:ZL201911186586.4

15.刘振国,胥保华,刘锋,崔学沛,郗学鹏,王颖,王红芳,王光明. 一种杆体可伸缩定位的收蜂笼. 实用新型专利,专利号:ZL202020734960.1

制定的标准:

1.胥保华,康明江,刘锋等. 蜜蜂群势增长期饲养技术规范(DB37/T 2520-2014,山东省地方标准)

2.胥保华,康明江,刘锋等. 蜜蜂传染性病害防治规范(DB37/T 2518-2014,山东省地方标准)

3.胥保华,刘锋,王颖. 蜜蜂代用花粉饲料生产技术规范(DB37/T 2519-2014,山东省地方标准)

4.胥保华, 康明江,刘锋等. 蜜蜂饲粮使用管理规范(DB37/T 2521-2014,山东省地方标准)

5.胥保华,刘锋,王颖. 中华蜜蜂饲养技术规范(DB37/T 2523-2014,山东省地方标准)

6.胥保华,康明江,刘锋等. 取蜜期蜂群管理规范(DB37/T 2522-2014,山东省地方标准)

7.李有志,胥保华,陶安勇等. 标准化蜂场建设技术规范(DB 37/T 3089-2017,山东省地方标准)

发表的文章(近三年)

1. Guo D, Zhao G, Li G, Wang C, Wang H, Liu Z, Xu B*, Guo X. Identification of a mitogen-activated protein kinase kinase (AccMKK4) from Apis cerana cerana and its involvement in various stress responses. Insect Mol Biol. 2021; 30(3):325-339. doi: 10.1111/imb.12698

2. Meng J, Wang L, Wang C, Zhao G, Wang H, Xu B*, Guo X. AccPDIA6 from Apis cerana cerana plays important roles in antioxidation. Pestic Biochem Physiol. 2021; 175:104830. doi: 10.1016/j.pestbp.2021.104830.

3. Chi X, Liu Z, Wang H, Wang Y, Wei W, Xu B*. Royal jelly enhanced the antioxidant activities and modulated the gut microbiota in healthy mice. J Food Biochem. 2021; 45(5):e13701. doi: 10.1111/jfbc.13701.

4. Zhao H, Li G, Guo D, Li H, Liu Q, Xu B*, Guo X. Response mechanisms to heat stress in bees. Apidologie, 2021, 52:388-399. DOI: 10.1007/s13592-020-00830-w.

5. Chi X, Liu Z, Wang H, Wang Y, Xu B*, Wei W. Regulation of a New Type of Selenium-Rich Royal Jelly on Gut Microbiota Profile in Mice. Biol Trace Elem Res. 2021; 25. doi: 10.1007/s12011-021-02800-4.

6. Hu X, Zhang W, Chi X, Wang H, Liu Z, Wang Y, Ma L, Xu B*. Non-targeted lipidomics and transcriptomics analysis reveal the molecular underpinnings of mandibular gland development in Apis mellifera ligustica. Dev Biol. 2021; 479:23-36. doi: 10.1016/j.ydbio.2021.07.016.

7. Chi X, Liu Z, Wei W, Hu X, Wang Y, Wang H, Xu B*. Selenium-rich royal jelly inhibits hepatocellular carcinoma through PI3K/AKT and VEGF pathways in H22 tumor-bearing mice. Food Funct. 2021; 12(19):9111-9127. doi: 10.1039/d1fo01070k.

8. Zhao G, Meng J, Wang C, Wang L, Wang H, Tian M, Ma L, Guo X, Xu B*. Roles of the protein disulphide isomerases AccPDIA1 and AccPDIA3 in response to oxidant stress in Apis cerana cerana. Insect Mol Biol. 2021; 28. doi: 10.1111/imb.12733.

9. Wang Y, Li Z, Ma L, Li G, Han K, Liu Z, Wang H, Xu B*. The Native Dietary Habits of the Two Sympatric Bee Species and Their Effects on Shaping Midgut Microorganisms. Front Microbiol. 2021; 12:738226. doi: 10.3389/fmicb.2021.738226.

10. Zhao G, Zhang X, Guo D, Wang H, Guo H, Tian M, Sun Q, Li H, Xu B*, Guo X. Identification and characterization of an Apis cerana cerana nucleoside diphosphate kinase (AccNDPK) associated with oxidative stress. Pestic Biochem Physiol. 2021; 178:104926. doi: 10.1016/j.pestbp.2021.104926.

11. Yu J, Zhang W, Chi X, Chen W, Li Z, Wang Y, Liu Z, Wang H, Xu B*. The dietary arachidonic acid improved growth and immunity of honey bee (Apis mellifera ligustica). Bull Entomol Res. 2021; 8:1-10. doi: 10.1017/S0007485321000821.

12. Zhao G, Zhao W, Cui X, Xu B, Liu Q, Li H, Guo X. Identification of an MGST2 gene and analysis of its function in antioxidant processes in Apis cerana cerana. Arch Insect Biochem Physiol. 2021; 106(4):e21770. doi: 10.1002/arch.21770.

13. Guo HJ, Wang LJ, Wang C, Guo DZ, Xu BH, Guo XQ, Li H. Identification of an Apis cerana zinc finger protein 41 gene and its involvement in the oxidative stress response. Arch Insect Biochem Physiol. 202; 108(1):e21830. doi: 10.1002/arch.21830.

14. Chen WF, Wang Y, Zhang WX, Liu ZG, Xu BH, Wang HF. Methionine as a methyl donor regulates caste differentiation in the European honey bee (Apis mellifera). Insect Sci. 2021; 28(3):746-756.

15. CHI X P, WEI W, ZHANG W X, LIU Z G, WANG H F, XU B H. Sodium Selenium Enhances the Antioxidative Activities and Immune Functions of Apis mellifera (Hymenoptera: Apidae) and Increases the Selenium Content in Royal Jelly. Environmental Entomology, 2020, 49(1): 169-177. DOI: 10.1093/ee/nvz131

16. CHEN W F, WANG Y, ZHANG W X, LIU Z G, XU B H, WANG H F. Methionine as a methyl donor regulates caste differentiation in the European honey bee (Apis mellifera). Insect Science, 2020. DOI 10.1111/1744-7917.12788

17. ZHAO H, LI G L, GUO D Z, WANG Y, LIU Q X, GAO Z, WANG H F, LIU Z G, GUO X Q, XU B H. Transcriptomic and metabolomic landscape of the molecular effects of glyphosate commercial formulation on Apis mellifera ligustica and Apis cerana cerana. Science of the Total Environment, 2020, 744. https://doi.org/10.1016/j.scitotenv.2020.140819

18. LI G L, ZHAO H, GUO H B, WANG Y, CUI X P, XU B H, GUO X Q. Functional and transcriptomic analyses of the NF Y family provide insights into the defense mechanisms of honeybees under adverse circumstances. Cellular and Molecular Life Sciences, 2020, 77(23): 4977–4995. https://doi.org/10.1007/s00018-019-03447-0

19. LI G L, ZHAO H, GUO H B, WANG Y, CUI X P, LI H, XU B H, GUO X Q. Analyses of the function of DnaJ family proteins reveal an underlying regulatory mechanism of heat tolerance in honeybee. Science of the Total Environment, 2020, 716. https://doi.org/10.1016/j.scitotenv.2020.137036

20. HONG W, XU B H, CHI X P, CUI X P, YAN Y F, LI T Y. Long-term and Extensive Monitoring for Bee Colonies based on Internet of Things. IEEE INTERNET OF THINGS JOURNAL, 2020, 7(8): 7148-7155. DOI: 10.1109/JIOT.2020.2981681

21. WANG H F, LIU Z G, WANG Y, MA L T, ZHANG W X, XU B H. Genome-Wide Differential DNA Methylation in Reproductive, Morphological, and Visual System Differences Between Queen Bee and Worker Bee (Apis mellifera). Frontiers in Genetics, 2020, 11: 770-770. DOI: 10.3389/fgene.2020.00770

22. LIU Z G, LIU F, LI G L, CHI X P, WANG Y, WANG H F, MA L T, HAN K, ZHAO G D, GUO X Q, XU B H. Metabolite Support of Long-Term Storage of Sperm in the Spermatheca of Honeybee (Apis mellifera) Queens. Frontiers in Physiology, 2020, 11:574856. DOI: 10.3389/fphys.2020.574856

23. WANG H F, LIU C L, LIU Z G, WANG Y, MA L T, XU B H. The different dietary sugars modulate the composition of the gut microbiota in honeybee during overwintering. BMC Microbiology, 2020, 20(1): S80-S95. https://doi.org/10.1186/s12866-020-01726-6

24. CUI X P, WANG C, WANG X X, LI G L, LIU Z G, WANG H F, GUO X Q, XU B H. Molecular Mechanism of the UDP-Glucuronosyltransferase 2B20-like Gene (AccUGT2B20-like) in Pesticide Resistance of Apis cerana cerana. Frontiers in Genetics, 2020, 11: 592595. DOI: 10.3389/fgene.2020.592595

25. GAO L J,WANG L J, YANG X X, WANG Y, LIU Z G, XU B H, GUO X Q. Role of a serine protease gene (AccSp1) from Apis cerana cerana in abiotic stress responses and innate immunity. Cell Stress and Chaperones, 2019, 24(1): 29-43.  https://doi.org/10.1007/s12192-018-0934-x  2019

26. WANG L J, WANG C, LI H, YANG X X, WANG Y, GUO X Q, XU B H. Isolation of AccGalectin1 from Apis cerana cerana and its functions in development and adverse stress response. Journal of Cellular Biochemistry. 2019;120(1): 671-684.

27. WANG X X, CHAO Y Z, WANG Y, XU B H, WANG C, LI H. Identification of an adaptor protein-2 mu gene (AccAP2m) in Apis cerana cerana and its role in oxidative stress responses. J Cell Biochem, 2019, 120(10): 16600-16613. DOI: 10.1002/jcb.28919

28. QIN M, WANG H F, LIU Z G, WANG Y, ZHANG W X, XU B H. Changes in cold tolerance during the overwintering period in Apis mellifera ligustica. Journal of Apicultural Research, 2019, 58(5): 702-709. DOI: 10.1080/00218839.2019.1634461

29. ZHANG W X, YAO Y F, WANG H F, LIU Z G, MA L T, WANG Y, XU B H. The Roles of Four Novel P450 Genes in Pesticides Resistance in Apis cerana cerana Fabricius: Expression Levels and Detoxification Efficiency. Front Genet, 2019, 10: 1000

30. ZHAO W C, CHAO Y Z, WANG Y, WANG L J, WANG X X, LI H, XU B H. Role of AccMGST1 in oxidative stress resistance in Apis cerana cerana. Cell Stress and Chaperones, 2019, 24(4): 1-13.

31. ZHANG X M, LI G L, YANG X X, WANG L J, WANG Y, GUO X Q, LI H, XU B H. Identification of a DnaJC3 gene in Apis cerana cerana and its involvement in various stress responses. Pesticide Biochemistry and Physiology, 2019, 160: 171-180.

出版专著

 1.《蜂产品知识》,李勇、胥保华编著,山东大学出版社,2002年。

 2.《实用养蜂学》,曾志将、胥保华主编,江西科技出版社,1996年。

 3.《蜜蜂产品》,胥保华主编,山东科技出版社,1996年。

 4.《养蜂与蜂产品》,胥保华副主编 山东科技出版社,1997年。

 5.《养蜂学》(全国农业高等院校“十三五”统编教材),胥保华副主编,中国农业出版社,2017年。

 6.《蜜蜂产品学》(全国农业高等院校“十一五”统编教材),胥保华副主编,中国农业出版社,2010年。

 7.《中国蜜蜂学》,胥保华参编,中国农业出版社,2001年。

 8.《中国实用蜜蜂学》,胥保华参编,河南科技出版社,2004年。

 9.《高效养蜂技术200问》,张中印 胥保华 吴黎明,中国农业出版社,2019年。

 10.Molecular Response Mechanisms of Apis cerana cerana to AbioticStress》(《中华蜜蜂抵抗非生物胁迫的分子响应机制》),胥保华 郭兴启著, 科学出版社, 2019.